No, because that's not how LRR tires work. Much of the frictional drag comes from the bending of the sidewall rubber as you drive. By using high pressure and very thin rubber in the stock tires, the flexing is reduced and what little there is doesn't involve much rubber.
The mini-tires used for spares are thick, and even though they can be run at pretty high pressures, when they flex there is more rubber involved.
There are lots of other LRR tire design considerations, too, but the bottom line is that the stock 165/65R14 tires are the lowest (known) rolling resistance tires available. Solar powered racers use even better tires, but they run at extremely high pressure, don't fit on normal rims, and don't have DOT approval...